Principal Investigator: Tamara C. Tamas | Healing Hope International
MUSE TBI · AAV HIE · IVIG · Neurorehab
MUSE Stem Cell Therapy for TBI
NCT07326059
Enrolling Soon
MUSE-TBI-OBS | Observational Study
Sponsor: Healing Hope International
Study Type
Prospective Observational (no intervention administered)
Population
Ages 6–75 with chronic Traumatic Brain Injury (TBI)
Treatment
MUSE (Multilineage-differentiating Stress-Enduring) stem cell infusions received outside the U.S.
Follow-up
12 months
MUSE cells are a specialized subset of mesenchymal stem cells with neuroregenerative properties. Participants independently elect to receive MUSE cell infusions through international clinical programs. The study captures real-world evidence on neurological function, quality of life, activities of daily living, and adverse events.
AAV9-PHP.eB Gene Therapy for HIE / Cerebral Palsy
NCT07264166
Enrolling Soon
GEN-HOPE | International Observational Study
Sponsor: Healing Hope International
Study Type
International Observational Study
Population
Children with chronic Hypoxic Ischemic Encephalopathy (HIE) / Cerebral Palsy
Treatment
Intranasal 15-Gene AAV9-PHP.eB therapy administered through international programs
Delivery
Intranasal administration
GEN-HOPE evaluates a novel intranasal delivery approach using AAV9-PHP.eB, an adeno-associated viral vector carrying 15 therapeutic genes, in children with chronic HIE-related neurological injury. The study tracks neurological outcomes, developmental milestones, and safety data over time.
Intranasal IVIG for Long COVID
NCT06992401
Enrolling Soon
Observational Study
Sponsor: Healing Hope International
Study Type
Observational Study
Population
Long COVID patients undergoing intranasal IVIG treatment
Treatment
Intranasal Intravenous Immunoglobulin (IVIG) — administered intranasally through international programs
Focus
Neurological and immune outcomes
Intravenous immunoglobulin (IVIG) is an immunomodulatory therapy with established use in neurological and autoimmune conditions. This observational study evaluates the safety and outcomes of intranasal IVIG delivery in Long COVID patients, capturing real-world data on symptom improvement, neurological function, and adverse events.
Neurorehabilitation Outcomes Study
NCT07493096
Enrolling Soon
Observational Study
Sponsor: Healing Hope International
Study Type
Observational Study
Population
Patients with neurological conditions undergoing neurorehabilitation
Approach
Structured neurorehabilitation programs through international clinical programs
Focus
Functional recovery, quality of life, and neurological outcomes
This observational study evaluates the safety and outcomes of neurorehabilitation interventions in patients with neurological conditions. Data is collected on functional recovery, activities of daily living, quality of life, and adverse events over a structured follow-up period.
About the Principal Investigator
Tamara C. Tamas
Director of Clinical Research & Translational Programs (Founder)
Healing Hope International, Spring, TX
ORCID: 0000-0001-8213-6953
Tamara C. Tamas is a biochemist and clinical research professional specializing in regenerative medicine, neurological injury, and translational science. Her work focuses on advancing patient access to innovative therapies through observational studies, compassionate use frameworks, and global clinical collaboration. She leads clinical research initiatives through Healing Hope International, supporting the development and evaluation of emerging therapies including stem cell treatments, gene therapy approaches, immunomodulation, and multimodal neurorehabilitation. Her research interests include cerebral palsy, hypoxic ischemic encephalopathy (HIE), traumatic brain injury (TBI), and other complex neurological conditions. Her work emphasizes real-world data collection to better understand treatment outcomes and accelerate the translation of scientific innovation into accessible clinical pathways.
Follow her work in regenerative medicine, clinical research, and patient access
Website
www.tctamas.com
Organization
healinghopeinternational.com
LinkedIn
linkedin.com/in/tamaractamas
YouTube
youtube.com/@TamaraCTamas
X (Twitter)
x.com/TamaraCTamas
ORCID
orcid.org/0000-0001-8213-6953
All four observational studies are enrolling soon. For enrollment inquiries, visit healinghopeinternational.com or reach out directly through the links above.